Are airplanes sprayed with pesticides? Yes , some are . It depends on the country you’re flying into and its public health regulations. According to the Federal Aviation Administration,. It’s quite common from hot/humid countries inbound to Europe . I’ve had it with ORY-bound AF from caribbean, or LHR-bound from various other countries. WHO mandate that aircraft must be sprayed under certain conditions (such as SARS outbreaks) but otherwise I think that WHO rules state that it’s down to the individual countries involved. The disinfection of aircraft using pesticides is allowed under international law, but not all countries require airlines to do this. The United States Environmental Protection Agency (EPA) does not list approved any pesticides for use in passenger cabins on commercial aircraft . According to The World Health Organization (WHO) and the International Civil Aviation Organization, certain aircraft cabins are sprayed with a ‘quick-acting insecticide’ immediately before take-off, while passengers are on board. 4 days ago · Almost 50 countries require pesticide spraying on all or selected flights, apparently to prevent the importation of insects that either carry tropical disease or damage plant/animal health. The cabin may also be pre-treated in a country that does not require pesticide spraying. Airlines do not inform passengers prior to ticket purchase or flight.